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Gadobutrol (API)
Gadobutrol (CAS 770691-21-9), the macrocyclic, non-ionic gadolinium contrast agent API, at an assay of 98.0-102.0% on the anhydrous basis, with free gadolinium held to 0.0003%. For MRI contrast-agent formulation.

Cyclen (1,4,7,10-Tetraazacyclododecane)
Cyclen (1,4,7,10-tetraazacyclododecane, CAS 294-90-6) at 98% minimum, the twelve-membered macrocycle from which DOTA, DO3A and the macrocyclic gadolinium contrast agents are built. Supplied as a white to off-white powder.

Cyclen Tetrahydrochloride
Cyclen tetrahydrochloride (CAS 10045-25-7), the stable salt form of the cyclen macrocycle, at an assay of 98.0-102.0% with chloride at 40-45%. The easier-to-store route into DOTA, DO3A and macrocyclic chelator synthesis.

DOTA (Tetraxetan)
DOTA (tetraxetan, CAS 60239-18-1) at 98% minimum purity, the octadentate macrocyclic chelator that forms the gadolinium complex of gadoterate and anchors radiometals in DOTA-based radiopharmaceuticals.

DO3A Trisodium Salt
DO3A trisodium salt (CAS 217973-03-0), the cyclen triacetate with one ring nitrogen left free: the branch point for the macrocyclic contrast agents gadoteridol and gadobutrol. Specification agreed with the quotation.

Cyclen Butanetriol Tetrahydrochloride (Gadobutrol Intermediate)
Cyclen butanetriol tetrahydrochloride (CAS 156077-56-4), the late-stage gadobutrol intermediate carrying the finished trihydroxy side chain, at 98% minimum with residual methanol and toluene held to ICH Q3C limits.

Gadoteric Acid (Gd-DOTA)
Gadoteric acid (Gd-DOTA, CAS 72573-82-1), the gadolinium complex of DOTA and the active moiety of gadoterate meglumine, the ionic macrocyclic MRI contrast agent. Specification agreed with the quotation.
![4,4-Dimethyl-3,5,8-trioxabicyclo[5.1.0]octane – Pharmaceutical intermediates product from Bio Green Chem](/_next/image?url=%2Fuploads%2Fnews%2Fchem-dimethyl-trioxabicyclooctane-pack-20260925-v1.webp&w=3840&q=75)
4,4-Dimethyl-3,5,8-trioxabicyclo[5.1.0]octane
4,4-Dimethyl-3,5,8-trioxabicyclo[5.1.0]octane (CAS 57280-22-5), the acetonide-protected meso epoxide that supplies gadobutrol's side chain. Offered in 98%, 99% and 99.9% grades as a colourless to pale yellow liquid.

2-Fluoro-N-methyl-4-nitrobenzamide
2-Fluoro-N-methyl-4-nitrobenzamide (CAS 915087-24-0), the nitro precursor of 4-amino-2-fluoro-N-methylbenzamide, which forms the benzamide half of the prostate cancer drugs enzalutamide and apalutamide. Specification agreed with the quotation.

Peramivir Isoxazoline Intermediate
The isoxazoline peramivir intermediate (CAS 229613-93-8, C18H30N2O5), formed by nitrile oxide cycloaddition and carrying the stereochemistry of the drug's ring. Supplied at 98% minimum with the diastereoisomer held to 0.1%.

Triphenylacetic Acid
Triphenylacetic acid (CAS 595-91-5) at an assay of 98.0-102.0%, the bulky carboxylic acid behind dirhodium triphenylacetate catalysts, with its decarboxylation product triphenylmethane held to 0.30%.

Bromocyclopropane
Bromocyclopropane (cyclopropyl bromide, CAS 4333-56-6) at 98% minimum with water held to 0.5%. The standard entry point to cyclopropyl Grignard reagents and cyclopropylboronic acid for installing cyclopropyl groups in drug and crop-protection molecules.

3-Iodooxetane
3-Iodooxetane (CAS 26272-85-5) at 98% minimum, identity confirmed by proton NMR. A reactive building block for attaching the oxetan-3-yl ring, the compact polar replacement for gem-dimethyl and carbonyl groups in drug design.

2-Methyl-3-(trifluoromethyl)aniline
2-Methyl-3-(trifluoromethyl)aniline (CAS 54396-44-0), the substituted aniline that forms the aryl half of the veterinary anti-inflammatory flunixin. A fluorinated building block for pharmaceutical and agrochemical synthesis; specification agreed with the quotation.