Yes. Both are classified in the EU as toxic for reproduction category 1B with hazard statements H360FD, and both are subject to REACH restriction. They share a metabolic route, being oxidised to alkoxyacetic acids that cause the reproductive and haematological effects, which is why the short-chain ethylene glycol ethers are regulated as a group rather than individually.
2
How does EE differ technically from EM?
Only modestly. The ethyl group adds one carbon relative to the methyl, which raises the boiling point, slows evaporation slightly and gives marginally stronger solvency for resins while reducing water affinity a little. Those differences are real but small, and they do not offset the shared toxicological classification, which is why both have been displaced together.
3
What is the substitute for EE?
Propylene glycol ethyl ether, PE, is the closest propylene-series equivalent and offers comparable solvency and evaporation behaviour without the reproductive toxicity classification. Depending on the formulation, PM or a glycol ether acetate may also serve. The choice should be made on the required evaporation rate and resin solubility rather than by name alone.
4
Is EE still supplied?
Yes, for permitted industrial uses where an authorisation or exemption applies, including certain coatings, inks, cleaning formulations, aviation de-icing and chemical synthesis. Supply is conditional on the end use being permitted in the destination market, and exposure controls including skin protection should be in place given its dermal absorption.
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