Sodium Hyaluronate

About This Product

Sodium hyaluronate is the sodium salt of hyaluronic acid, a glycosaminoglycan built from repeating disaccharide units of D-glucuronic acid and N-acetyl-D-glucosamine. It carries CAS number 9067-32-7 and the INCI name Sodium Hyaluronate, and is produced commercially by bacterial fermentation. The salt is more stable and far more soluble than the free acid, which is why it is the form used in manufacturing. Molecular weight is the specification that determines behaviour, and grades span three orders of magnitude. High molecular weight material, above about one million daltons, builds viscosity and forms a surface film that reduces transepidermal water loss. Low molecular weight and hydrolysed grades give a lighter, less tacky feel and are marketed for distribution deeper into the upper skin layers. Solutions are stable across roughly pH 4 to 9; strong acid, strong alkali, heat and oxidising agents degrade the chain and collapse viscosity. In formulation it is used at 0.05 to 1 percent, dispersed slowly onto moving water or pre-blended with glycerine, since the powder clumps if dropped into still water, and added during cool-down because hydration takes time rather than heat. It is used in serums, moisturisers and masks, eye and lip care, sun and after-sun products, and in medical device and ophthalmic applications. Bio Green Chem supplies sodium hyaluronate to specification on molecular weight range, assay, appearance, loss on drying, protein, endotoxin and microbiology.