MPEG - Polyethylene Glycol Monomethyl Ether

About This Product

Polyethylene glycol monomethyl ether, MPEG, has CAS number 9004-74-4 and is supplied in molecular weight grades from a few hundred to several thousand, ranging from viscous liquids to waxy solids. Grade is stated as an average molecular weight, since the material is a distribution rather than a single compound. The single capped end is the whole design. Ordinary polyethylene glycol carries a hydroxyl at each end, so any reaction with it can occur at either or both, producing crosslinks and a mixture of products. MPEG has one end blocked with a methyl group and one reactive hydroxyl, so it can be attached to something else at a single defined point. That monofunctionality is what allows PEGylation, the attachment of PEG chains to proteins and drug molecules to extend circulation time and reduce immunogenicity, and it is equally important in surfactant manufacture, where a PEG chain must be grafted to a hydrophobe without bridging two of them. Pharmaceutical grades are specified on polydispersity, residual ethylene oxide and dioxane, and metals, well beyond industrial requirements. It is used in PEGylated pharmaceuticals, non-ionic surfactants and dispersants, concrete superplasticisers, cosmetics and as a polymer intermediate. Bio Green Chem supplies MPEG grades to specification on average molecular weight, hydroxyl value, polydispersity, water, pH and residual monomer.